As it is the 2nd to the last casino/hotel to the end of the Southern end of the Strip, you will have a farther way to go to see the other casinos on the strip. If it is your intent to mainly visit those on the strip, I would stay more central, such as Bally's/Paris, Harrahs, Mirage, etc.
If your intent is to go off strip or downtown, then the Luxor would probably work out. If you do not have a car and plan to take public transit, it being down that end should work in your favor. Especially when taking the Deuce downtown. This is the bus that runs along the strip and then on into the city towards Freemont Street. As it gets further down the strip towards the city proper it can get extremely full. If you pick it up at the LV Blvd/Tropicana intersection, which is near where you will be, you can usually get on with no problems. almost 5 years ago
The Luxor itself is a Vegas site. ;-)
It depends if you have a car, and how long you plan on staying. There is a LOT in Vegas to see. It can easily take a week to see it all. The Luxor happened to be the first place I stayed in Vegas. (I've been there 20 times since).
If you are on foot, and are staying the typical 2 or 3 days, then the Luxor is a good place to see the whole Southern and Mid strip. I would abandon downtown and Fremont until your second trip.
Like the poster before said - Luxor is the second last Southern hotel on the Strip, but there is a lot to see in the South and Mid strip. almost 5 years ago
It's on the strip, but it can be difficult to get to the further end. Still, cabs are cheap and it would only take a few minutes. Plus, you're right by the 'welcome to Las Vegas' sign and close to the airport too.
I stayed here for a week in 2011 so the location was fine. However, if you're going for a short period of time and want to see a lot of the other hotels/casinos, Monte Carlo is a good choice. Slightly more central, still luxury but costs about half the price of the other high end hotels. I've stayed here too and it was good! almost 5 years ago