Grasshoppers right next to the Central Station is brand new and receiving fab reviews - seems a good location and budget combo : http://www.grasshoppersglasgow.com/
Hotel du Vin is lovely.
Premier Inn on George Square.
Not sure of your budget? about 6 years ago
Motre great Hotels in Glasgow:-
Mal Maison - very stylish, without being horribly expensive. Close to everything. Really cool basement bar, with lots of good whiskys.
Babbity Bowster - Glasgow cool, great beer, great scottish food, right in the heart off the Merchant City. Check their web-site. about 6 years ago