I like the Old Town area, near Zurich Central, across from the train station. Great walking area, along the area and some very cool bars. There are plenty of mid-range hotels in the area. Hotel Limmathof is a great location if you want no frills. about 9 years ago
It depends as always on what you like. The neighbourhood of the Hotel Greulich is a mixture of all ethnics and classes but it is very much Zurich as it is for the people who live there. I would recommend the hotel Greulich.
http://www.hotel-greulich.ch/en/hotel_zurich_cityhotel_zurich_hotel_central_lakezurich_airport.aspx almost 9 years ago